教育背景
1998-2003, 清华大学, 机械工程系，硕士、博士
1994-1998, 清华大学, 机械工程, 学士
工作履历
2020-至今, 清华大学, 机械工程系, 长聘副教授，特别研究员
2013-2018, 第四军医大学, 全军骨科研究所, 客座教授
2013-2015, 清华大学, 深圳研究生院, 兼职教授
2013-2016, 军事医学科学院, 基础医学研究所, 客座研究员
2012-2020, 共青团北京市委员会, 书记、副书记
2010-2012, 北京市西城区人民政府金融街街道，党工委书记、主任
2010，经清华大学专业技术评审委员会审定，晋升教授
2005-2010, 清华大学, 机械工程系, 副教授
2002-2005, 清华大学, 机械工程系, 讲师
2003-2005, 清华大学, 博士后
2001-2002, 清华大学, 机械工程系, 研究实习员
教学工作
本科生课程：生物材料工程与器件（00120112）
科研工作
研究方向：
生物3D打印
复杂组织器官再生
肿瘤体外模型
空间生物3D打印
DNA存储技术
增材制造
研究概况：
熊卓博士长期从事生物3D打印等领域的研究工作。现任北京机械工程学会副理事长，北京市生物制造及快速成形重点实验室副主任。曾担任中国机械工程学会理事、中国宇航学会航天医学工程与空间生物学专业委员会委员等学术兼职，负责筹建中国机械工程学会生物制造分会并担任首届常务委员/总干事。
从1999年开始从事组织工程支架的3D打印研究，发明了生物材料低温沉积制造工艺并获得发明专利（ZL001249851）。是国际上最早开展细胞3D打印的研究者之一，率先提出基于单元受控堆积成形的细胞3D打印技术并获得首个发明专利（ZL 200410009787.4），2004年主持了国家自然科学基金委在细胞3D打印领域的第一个资助项目（No.30400099）。2005年发表论文提出“生物制造工程”，系统阐述了其原理与方法。在组织工程支架制造、细胞3D打印和组织器官仿生构建等方面进行了深入的研究，发明的低温沉积制造工艺广泛应用于组织工程支架成形，发明了多种细胞3D打印工艺，相关成果两次被教育部鉴定为国际领先水平，多款设备实现了商品化生产。
发表学术论文百余篇，近年来在Advanced Functional Materials、Biomaterials、 Small和Biofabrication等期刊发表多篇论文，论文被引用3100余次，H因子32（Scopus）。获得发明专利授权27项，多项专利成果已转化。担任Advanced Materials，Advanced Healthcare materials和Small等期刊特邀审稿人。主持国家自然科学基金联合基金重点项目、面上项目和青年基金项目等多个国家级、省部级项目（课题）。曾获北京市科学技术奖一项。
论文与专利
1. 主要论著
a. 期刊论文:
1. Xia, J., Xiong, Z., Guo, J., Wang, Y., Luo, Y., Sun, Y., Guo, Z., Lu, B., Zhang, T., Sun, W. Study of paraquat-induced pulmonary fibrosis using biomimetic micro-lung chips. Biofabrication. 2023, 15: 104104
2. Fang, Y., Sun, W., Zhang, T. and Xiong, Z. Recent advances on bioengineering approaches for fabrication of functional engineered cardiac pumps: A review. Biomaterials. 2022, 280: 121298
3. Zhang, Y., Wang, Z., Hu, Q., Luo, H., Lu, B., Gao, Y., Qiao, Z., Zhou, Y., Fang, Y., Gu, J., Zhang, T. and Xiong, Z. 3D Bioprinted GelMA-Nanoclay Hydrogels Induce Colorectal Cancer Stem Cells Through Activating Wnt/β-Catenin Signaling. Small. 2022, 18(18): 2200364
4. Ji, J., Wang, C., Xiong, Z., Pang, Y. and Sun, W. 3D-printed scaffold with halloysite nanotubes laden as a sequential drug delivery system regulates vascularized bone tissue healing. Materials Today Advances. 2022, 15: 100259
5. Mo, X., Ouyang, L., Xiong, Z., Zhang, T. Advances in digital light processing of hydrogels. Biomedical Materials (Bristol). 2022, 17(4) 042002
6. Fang, Y., Guo Y., Liu, T., Xu, R., Mao, S., Mo, X., Zhang, T., Ouyang, L., Xiong, Z., Sun, W. Advances in 3D Bioprinting. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers. 2022, 1(1): 100011
7. Xu, Y., Wang, C., Yang, Y., Liu, H., Xiong, Z., Zhang, T., Sun, W. A Multifunctional 3D Bioprinting System for Construction of Complex Tissue Structure Scaffolds: Design and Application. International Journal of Bioprinting. 2022, 8(4): 617
8. Liu, T., Zhou, C., Shao, Y., Xiong, Z., Weng, D., Pang, Y., Sun, W. Construction and Application of in vitro Alveolar Models Based on 3D Printing Technology. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers. 2022, 1(1):100025
9. Ye, M., Lu, B., Zhang, X., Li, B., Xiong, Z., Zhang, T. Coaxial Embedded Printing of Gelatin Methacryloyl–alginate Double Network Hydrogel for Multilayer Vascular Tubes. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers. 2022, 1(1):100024
10. Fang, Y., Guo, Y., Ji, M., Li, B., Guo, Y., Zhu, J., Zhang, T., and Xiong, Z. 3D Printing of Cell-laden Microgel-based Biphasic Bioink with Heterogeneous Microenvironment for Biomedical Applications. Advanced Funtional Materials. 2021,31(51):2109810
11. Lu, B., Li M., Fang, Y., Liu, Z., Zhang, T., and Xiong, Z. Rapid fabrication of cell-laden microfibers for construction of aligned biomimetic tissue. Frontiers in Bioengineering and Biotechnology. 2021, 8: 610249
12. Li, ZY., Jia, SJ., Xiong, Z., Long, QF., Yan, SR., Hao, F., Liu, J., Yuan, Z. 3D-printed scaffolds with calcified layer for osteochondral tissue engineering. Journal of Bioscience and Bioengineering, 2018, 126(3): 389-396.
13. Jia, S. &, Wang, J., Zhang, T., Pan, W., Li, Z., He, X., Yang, C., Wu, Q., Sun, W., Xiong, Z., Hao, D. Multilayered Scaffold with a Compact Interfacial Layer Enhances Osteochondral Defect Repair. ACS Applied Materials and Interfaces, 2018, 10, 20296–20305.
14. Zhang, T., Zhang, H., Zhang, L., Jia, S., Liu, J., Xiong, Z., & Sun, W. Biomimetic design and fabrication of multilayered osteochondral scaffolds by low-temperature deposition manufacturing and thermal-induced phase-separation techniques, Biofabrication, 2017, 9(2).
15. Jia, S.&, Zhang, T., Xiong, Z., Pan, W., Liu, J., and Sun, W. In vivo evaluation of a novel oriented scaffold-BMSC construct for enhancing full-thickness articular cartilage repair in a rabbit model. PLoS ONE, 2015, 10.
16. Zhang, T., Jin, L., Fang, Y., Lin, F., Sun, W., and Xiong, Z. Fabrication of biomimetic scaffolds with oriented porous morphology for cardiac tissue engineering. Journal of Biomaterials and Tissue Engineering,2014, 4, 1030–1039.
17. Da, H.&, Jia, S.J.&, Meng, G.L., Cheng, J.H., Zhou, W., Xiong, Z., Mu, Y.J., and Liu, J. The Impact of Compact Layer in Biphasic Scaffold on Osteochondral Tissue Engineering. PLoS ONE, 2013, 8(1)
18. Zhang, T.&, Wan, L.Q., Xiong, Z., Marsano, A., Maidhof, R., Park, M., Yan, Y., and Vunjak-Novakovic, G. Channelled scaffolds for engineering myocardium with mechanical stimulation. Journal of Tissue Engineering and Regenerative Medicine 2012, 6, 748–756.
19. Wang, C., Meng, G., Zhang, L., Xiong, Z., and Liu, J. Physical properties and biocompatibility of a core-sheath structure composite scaffold for bone tissue engineering in vitro. Journal of Biomedicine and Biotechnology, 2012.
20. Jia, S.&, Liu, L., Pan, W., Meng, G., Duan, C., Zhang, L., Xiong, Z., and Liu, J. Oriented cartilage extracellular matrix-derived scaffold for cartilage tissue engineering. Journal of Bioscience and Bioengineering, 2012, 113, 647–653.
21. Xia, Y., Mei, F., Duan, Y., Gao, Y., Xiong, Z., Zhang, T., and Zhang, H. Bone tissue engineering using bone marrow stromal cells and an injectable sodium alginate/gelatin scaffold. Journal of Biomedical Materials Research - Part A, 2012, 100 A, 1044–1050.
22. Hao, W., Pang, L., Jiang, M., Lv, R., Xiong, Z., and Hu, Y.Y. Skeletal repair in rabbits using a novel biomimetic composite based on adipose-derived stem cells encapsulated in collagen I gel with PLGA-β-TCP Scaffold. Journal of Orthopaedic Research, 2010, 28, 252–257.
23. Makitie, A.A., Yan, Y., Wang, X., Xiong, Z., Paloheimo, K.S., Tuomi, J., Paloheimo, M., Salo, J., and Renkonen, R. In vitro evaluation of a 3D PLGA-TCP composite scaffold in an experimental bioreactor. Journal of Bioactive and Compatible Polymers, 2009, 24, 75–83.
24. Liu, L., Xiong, Z., Yan, Y., Zhang, R., Wang, X., and Jin, L. Multinozzle low-temperature deposition system for construction of gradient tissue engineering scaffolds. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2009, 88, 254–263
25. Ma, X., Wu, X., Wu, Y., Liu, J., Xiong, Z., Lv, R., Yan, Y., Wang, J., and Li, D. Posterolateral spinal fusion in rabbits using a RP-based PLGA/ TCP/Col/BMSCs-OB biomimetic grafting material. Journal of Bioactive and Compatible Polymers, 2009, 24, 457–472.
26. Ma, X., Wu, X., Hu, Y., Xiong, Z., Lv, R., Wang, J., Li, D., and Yan, Y. Intervertebral spinal fusion using a RP-based PLGA/TCP/ bBMP biomimetic grafting material. Journal of Bioactive and Compatible Polymers, 2009, 24, 146–157.
27. Li, S.&, Yan, Y., Xiong, Z., Weng, C., Zhang, R., and Wang, X. Gradient hydrogel construct based on an improved cell assembling system. Journal of Bioactive and Compatible Polymers,2009, 24, 84–99.
28. Li, S., Xiong, Z., Wang, X., Yan, Y., Liu, H., and Zhang, R. Direct fabrication of a hybrid cell/hydrogel construct by a double-nozzle assembling technology. Journal of Bioactive and Compatible Polymers, 2009, 24(3), 249–265.
29. Liu, L.&, Xiong, Z., Zhang, R., Jin, L., and Yan, Y. A novel osteochondral scaffold fabricated via multi-nozzle low-temperature deposition manufacturing. Journal of Bioactive and Compatible Polymers, 2009, 24, 18–30.
30. Yu, D., Li, Q., Mu, X., Chang, T., and Xiong, Z. Bone regeneration of critical calvarial defect in goat model by PLGA/TCP/rhBMP-2 scaffolds prepared by low-temperature rapid-prototyping technology. International Journal of Oral and Maxillofacial Surgery, 2008, 37, 929–934.
31. Hao, W., Hu, Y.Y., Wei, Y.Y., Pang, L., Lv, R., Bai, J.P., Xiong, Z., and Jiang, M. Collagen I gel can facilitate homogenous bone formation of adipose-derived stem cells in PLGA-β-TCP scaffold. Cells Tissues Organs, 2008, 187, 89–102.
32. Cheng, J., Lin, F., Liu, H., Yan, Y., Wang, X., Zhang, R., and Xiong, Z. Rheological properties of cell-hydrogel composites extruding through small-diameter tips. Journal of Manufacturing Science and Engineering, Transactions of the ASME, 2008, 130, 0210141–0210145.
33. Liu, L., Xiong, Z., Yan, Y., Hu, Y., Zhang, R., and Wang, S. Porous morphology, porosity, mechanical properties of poly(α-hydroxy acid)-tricalcium phosphate composite scaffolds fabricated by low-temperature deposition. Journal of Biomedical Materials Research - Part A, 2007, 82, 618–629.
34. Zhang, T., Yan, Y., Wang, X., Xiong, Z., Lin, F., Wu, R., and Zhang, R. Three-dimensional gelatin and gelatin/hyaluronan hydrogel structures for traumatic brain injury. Journal of Bioactive and Compatible Polymers, 2007, 22, 19–29.
35. Pang, L., Hu, Y., Yan, Y., Liu, L., Xiong, Z., Wei, Y., and Bai, J. Surface modification of PLGA/β-TCP scaffold for bone tissue engineering: Hybridization with collagen and apatite. Surface and Coatings Technology, 2007 201, 9549–9557.
36. Xu, W., Wang, XH., Yan, YN., Zheng, W., Xiong, Z., Lin, F., Wu, RD., Zhang, RJ. Rapid prototyping three-dimensional cell/gelatin/fibrinogen constructs for medical regeneration. Journal of Bioactive and Compatible Polymers. 2007, 22(4):363-377
37. Yang, F., Cui, W., Xiong, Z., Liu, L., Bei, J., and Wang, S. Poly(l,l-lactide-co-glycolide)/tricalcium phosphate composite scaffold and its various changes during degradation in vitro. Polymer Degradation and Stability, 2006, 91, 3065–307.
38. Wang, X., Yan, Y., Pan, Y., Xiong, Z., Liu, H., Cheng, J., Liu, F., Lin, F., Wu, R., Zhang, R., Lu, Q. Generation of three-dimensional hepatocyte/gelatin structures with rapid prototyping system. Tissue Engineering, 2006, 12, 83–90.
39. Yu, X., Bichtelen, A., Wang, X., Yan, Y., Lin, F., Xiong, Z., Wu, R., Zhang, R., and Lu, Q. Collagen/chitosan/heparin complex with improved biocompatibility for hepatic tissue engineering. Journal of Bioactive and Compatible Polymers, 2005, 20, 15–28.
40. Yan, Y., Wang, X., Pan, Y., Liu, H., Cheng, J., Xiong, Z., Lin, F., Wu, R., Zhang, R., and Lu, Q. Fabrication of viable tissue-engineered constructs with 3D cell-assembly technique. Biomaterials, 2005, 26, 5864–5871.
41. Wang, X., Liang, X., Xiong, Z., Yan, Y., Zhang, R., Lin, F., Wu, RD., Lu, Q., Fan, Y. A dissolvable intralumental stent for sutureless vascular anastomosis. ASBM6: Advanced Biomaterials VI Series: Key Engineering Materials. 2005, 288-289:575-578
42. Wang, X., Yan, Y., Xiong, Z., Lin, F., Wu, R., Zhang, R., and Lu, Q. Preparation and evaluation of ammonia-treated collagen/chitosan matrices for liver tissue engineering. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2005, 75, 91–98.
43. Wang, X., Yan, Y., Lin, F., Xiong, Z., Wu, R., Zhang, R., and Lu, Q. Preparation and characterization of a collagen/chitosan/heparin matrix for an implantable bioartificial liver. Journal of Biomaterials Science, Polymer Edition, 2005, 16, 1063–1080.
44. Yan, Y., Wang, X., Xiong, Z., Liu, H., Liu, F., Lin, F., Wu, R., Zhang, R., Lu, Q. Direct construction of a three-dimensional structure with cells and hydrogel. Journal of Bioactive and Compatible polymers. 2005, 20(3) 259-269
45. Xiong, Z., Yan, Y., Zhang, R., Wang, X., Organism manufacturing engineering based on rapid prototyping principles. Rapid Prototyping Journal. 2005,11(3)
46. Yan, Y., Wu, R., Zhang, R., Xiong, Z., and Lin, F. Biomaterial forming research using RP technology. Rapid Prototyping Journal, 2003, 9, 142–149.
47. Hu, Y., Zhang, C., Zhang, S., Xiong, Z., and Xu, J. Development of a porous poly(L-lactic acid)/ hydroxyapatite/collagen scaffold as a BMP delivery system and its use in healing canine segmental bone defect. Journal of Biomedical Materials Research - Part A,2003, 67, 591–598.
48. Yan, Y., Xiong, Z., Hu, Y., Wang, S., Zhang, R., and Zhang, C. Layered manufacturing of tissue engineering scaffolds via multi-nozzle deposition. Materials Letters,2003, 57(18), 2623–2628.
49. Xiong, Z., Yan, Y., Wang, S., Zhang, R., and Zhang, C. Fabrication of porous scaffolds for bone tissue engineering via low-temperature deposition. Scripta Materialia ,2002, 46, 771–776.
50. Xiong, Z., Yan, Y., Zhang, R., and Sun, L. Fabrication of porous poly(L-lactic acid) scaffolds for bone tissue engineering via precise extrusion. Scripta Materialia, 2001, 45, 773–779.
b. 著作和书籍章节
1.张翼，熊卓，主编. 青年与社会发展——来自北京的调查. 中国社会科学出版社，2018年6月
2.杜汇良, 熊卓, 主编. 清华大学辅导员工作案例. 清华大学出版社, 2010年4月
3. 熊卓. 国（境）外高校学生辅导工作比较与借鉴.见: 张再兴 等, 著. 高校辅导员队伍建设理论与实践. 人民出版社，2010. 263-293
4.熊卓, 主编. 求索与创新-清华大学学生工作论文集（第13集）. 清华大学出版社，2008年3月
5. 熊卓, 李生杰. 生物制造工程研究成果向本科教学资源的转化. 见: 清华大学高等教育学会, 编. 清华大学科研成果转化为教学资源典型案例汇编. 清华大学出版社, 2007. 67~70
2. 代表性授权专利
1. 熊卓，方永聪，张婷，郭依涵，郭昱江. 一种构建复杂异质组织/器官的多级悬浮打印方法, 中国，ZL2021105262513.
2. 熊卓，方永聪，张婷. 一种构建具有异质功能纤维和血管通道的纤维束/组织结构的方法，中国，ZL2021105987630.
3. 熊卓，方永聪，张婷，鲁冰川. 一种具有仿生螺旋取向化微结构的人工心室及其制备方法，中国，ZL2021105988101.
4. 熊卓，张婷，张艳梅，莫兴武，鲁冰川. 一种适用于太空环境的细胞悬浮培养单元，中国，ZL2020114996579.
5. 熊卓，张婷，张艳梅，莫兴武，鲁冰川. 一种基于微卫星的细胞水凝胶三维培养装置，中国，ZL202011513449X.
6. 熊卓，张婷，张艳梅，莫兴武，鲁冰川. 一种基于微卫星的空间全自动多功能生物反应器，中国，ZL2020115134729.
7. 叶旻，张婷，熊卓，鲁冰川，骆浩. 一种可排卵的人工卵巢支架及其制备方法和应用，中国，ZL2022102486771
8. 熊卓，张婷，莫兴武，鲁冰川，张艳梅. 一种3D打印装置的封闭成形模块，中国，ZL2020109766365.
9. 熊卓，张婷，莫兴武，鲁冰川，张艳梅. 一种多模块串行生物3D打印装置，中国，ZL2020109764675.
10. 熊卓，张婷，莫兴武，鲁冰川，张艳梅. 一种基于微小卫星的遥控全自动生物3D打印系统，ZL2020109838128.
11. 熊卓，张婷，刘建，孟国林，张腊全，林峰，孙伟. 一种组织工程骨软骨复合支架及其制备方法, 中国，ZL2012103449085.
12.熊卓，黎铭峰，张婷，孙伟，张人佶，林峰. 一种组织工程纤维束结构体及其制备方法，中国，ZL2011103211655.
13. 熊卓，胡京奇，张婷，张人佶，林峰，颜永年. 灌注-灌流-脉动联合构建的组织工程心肌生物反应器，中国，ZL201010133838X.
14.熊卓，颜永年，李生杰，王小红，吴任东，林峰，张人佶，卢清萍，刘海霞. 一种基于仿生过程的水凝胶快速成形工艺方法，中国，ZL2006100115509.
15.颜永年，熊卓，王小红，林峰，吴任东，张人佶，卢清萍. 一种细胞－材料单元的三维受控堆积成形方法，中国，ZL2004100097874.
16.颜永年，张人佶，卢清萍，熊卓，史廷春，陈立峰，崔福斋，胡蕴玉，郑卫国，王笠. 无加热液化过程的挤压、喷射成形工艺方法，中国，ZL001249851
奖励与荣誉
2010 指导研究生胡京奇获清华大学优秀硕士论文
2008 指导研究生翁晨阳获清华大学优秀硕士论文
2006 北京市科学技术奖三等奖
2006 北京高校优秀辅导员
2003 清华大学优秀博士毕业生、优秀博士论文
2003 中日友好NSK机械工程论文奖
2002 清华大学林枫优秀辅导员奖
1998 清华大学优秀毕业生
